Britney on kerännyt yli miljoona dollaria Nevada Childhood Cancer Foundation -järjestölle. Varoja on kerätty POMin lipputuloista sekä erilaisilla tempauksilla, kuten XCYCLE-kampanjalla. Kerätyillä rahoilla avataan Britney Spears Campus, jossa voidaan hoitaa sairaita lapsia ja heidän omaisiaan. Syöpäsairaat ovat lähellä Britneyn sydäntä, sillä hänen tätinsä kuoli syöpään vuonna 2007.
“There are many things I’ve done in my career that I am proud of, but none more than this. The fact that I was able to use my celebrity status to raise the money to build this incredible facility to help sick children and their families when they need it the most not only brings many tears to my eyes, but really brings tremendous meaning to this amazing journey that I have been on. My aunt Sandra died of cancer and I know the devastating effects that this terrible disease brings upon its victims and their loved ones, but when it happens to innocent young children, there’s literally nothing I can think of worse than that. I’m just glad that I can help in some small way. I want to thank the NCCF for the amazing work they do on a daily basis and I look forward to being there to officially open the Britney Spears Campus of the Nevada Childhood Cancer Foundation in the fall.”